Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 9/20 | 0.70 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.70 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770007 | 0.91 | MAPK14 (0.71) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5771358 | 0.91 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5772525 | 0.91 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5770416 | 0.90 | MAPK14 (0.63) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5770318 | 0.90 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5768247 | 0.90 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5772707 | 0.90 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5771457 | 0.90 | MAPK14 (0.63) | MAPK13MAPK12MAPK11MAPK14PIK3CG | |
| SCHEMBL5773996 | 0.90 | MAPK14 (0.69) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5769551 | 0.90 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |