Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.58 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770594 | 0.89 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL6813458 | 0.84 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769927 | 0.83 | MAPK13 (0.66) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770592 | 0.80 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770993 | 0.80 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL5770916 | 0.79 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770200 | 0.78 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5773031 | 0.78 | MAPK13 (0.71) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5767956 | 0.78 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5773271 | 0.77 | MAPK13 (0.70) | MAPK13MAPK12MAPK11MAPK14SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989395-B2 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2006-01-24 | — | — | US | claimed |
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |
| US-6989395-B2 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2006-01-24 | — | — | US | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |