Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 10/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770170 | 0.91 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6075383 | 0.87 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5772998 | 0.87 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5769405 | 0.86 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5771209 | 0.86 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5771542 | 0.86 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5768923 | 0.85 | MAPK13 (0.50) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5768694 | 0.85 | MAPK13 (0.57) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5770808 | 0.85 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5769948 | 0.84 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |