SCHEMBL577155

SCHEMBL577155

O=C(NN1C(=O)c2ccccc2C1=O)c1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 1.00
PTGS2 P35354 1/20 1.00
LMNA P02545 4/20 0.55
KDM4E B2RXH2 8/20 0.54
MEN1 O00255 8/20 0.54
KMT2A Q03164 8/20 0.54
MAPT P10636 4/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
USP2 O75604 1/20 0.54
GAA P10253 2/20 0.52
MPO P05164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HIF1A Q16665 1/20 0.52
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
APEX1 P27695 1/20 0.48
HTT P42858 3/20 0.47
TP53 P04637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11810849 0.88 PTGS1 (0.78) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11806217 0.88 PTGS1 (0.78) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11828660 0.87 PTGS1 (0.76) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11808596 0.86 PTGS1 (0.75) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11808288 0.86 PTGS1 (0.75) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11812145 0.86 PTGS1 (0.75) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11812714 0.85 PTGS1 (0.74) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11813323 0.85 PTGS1 (0.74) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11817754 0.85 PTGS1 (0.74) PTGS1PTGS2LMNAKDM4EMEN1
SCHEMBL11808423 0.85 PTGS1 (0.74) PTGS1PTGS2LMNAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661931-A Automobile-used good-appearance anti-aging recycled polypropylene composite material and preparation method thereof 重庆会通科技有限公司 2025-03-21 CN claimed
CN-119161651-A Flame-retardant and aging-resistant polyolefin cable material, preparation method and cable prepared from cable material 深圳市沃尔核材股份有限公司 2024-12-20 CN claimed
CN-119119580-A Modified aluminum hydroxide, flame-retardant PE (polyethylene) and preparation method thereof, and cable prepared from PE material 深圳市沃尔核材股份有限公司 2024-12-13 CN claimed
CN-118507119-A Tensile cable and preparation method thereof 江西美园电缆集团有限公司 2024-08-16 CN claimed
CN-118406322-A Post-consumer regenerated polypropylene material with high heat resistance, and preparation method and application thereof 万华化学集团股份有限公司 2024-07-30 CN claimed
CN-114716819-B Polyamide composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2024-04-19 CN claimed
CN-117645751-B High-temperature-resistant copper conductor oxidation-resistant ultraviolet irradiation crosslinking polyethylene insulating material and preparation method thereof 河南云瀚实业有限公司 2024-04-16 CN claimed
CN-117645751-A High-temperature-resistant copper conductor oxidation-resistant ultraviolet irradiation crosslinking polyethylene insulating material and preparation method thereof 河南云瀚实业有限公司 2024-03-05 CN claimed
CN-116903987-A Composite material and preparation method and application thereof 东莞市奥能工程塑料有限公司 2023-10-20 CN claimed
CN-115947895-A Thermoplastic polypropylene direct-current cable insulating material and preparation method thereof 中国电力科学研究院有限公司 2023-04-11 CN claimed
CN-113563655-A Low-shrinkage one-step silane crosslinked polyethylene insulating material 杭州永通新材料有限公司 2021-10-29 CN claimed
CN-113480797-A Pre-crosslinking-resistant one-step silane crosslinked polyethylene insulating material for cables of 35kV and below, and environment-friendly preparation method and application thereof 合肥工业大学 2021-10-08 CN claimed
CN-113444268-A High-performance reinforced PP (polypropylene) material for automobile fan and preparation method thereof 横店集团得邦工程塑料有限公司 2021-09-28 CN claimed
CN-113150431-A 125 ℃ low-smoke halogen-free polyolefin cable material for locomotive wires and preparation method thereof 南京中超新材料股份有限公司 2021-07-23 CN claimed
CN-113105694-A Medium-voltage polypropylene cable and preparation method thereof 中国电力科学研究院有限公司 2021-07-13 CN claimed
CN-112920555-A TPEE composite material suitable for high-speed extrusion and preparation method thereof 宁波市青湖弹性体科技有限公司 2021-06-08 CN claimed
CN-109957190-B Environment-friendly polyvinyl chloride plastic for ultrathin-wall automobile wire, preparation method of environment-friendly polyvinyl chloride plastic and ultrathin-wall automobile wire 上海凯波电缆特材股份有限公司 2021-03-02 CN claimed
CN-112280159-A Functional additive composite master batch and preparation method and application thereof 天津金发新材料有限公司 2021-01-29 CN claimed
CN-111763374-A Semiconductive shielding material for polypropylene non-crosslinked cable and preparation method thereof 江阴市海江高分子材料有限公司 2020-10-13 CN claimed
EP-2418200-A1 PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF- MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES EMS S. A. (BR) 2012-02-15 EP claimed