Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460433 | 0.89 | PARP1 (0.57) | PARP1 | |
| SCHEMBL5458117 | 0.84 | PKN1 (0.45) | — | |
| SCHEMBL5463373 | 0.80 | PARP1 (0.64) | DHODHPARP1 | |
| SCHEMBL9725333 | 0.79 | DHODH (0.77) | DHODHPARP1 | |
| SCHEMBL1298432 | 0.74 | DHODH (0.94) | DHODHPARP1 | |
| SCHEMBL505661 | 0.72 | DHODH (1.00) | DHODHPARP1 | |
| SCHEMBL1298102 | 0.72 | DHODH (0.65) | DHODHPARP1 | |
| SCHEMBL10211812 | 0.71 | DHODH (0.82) | DHODHPARP1 | |
| SCHEMBL7474958 | 0.70 | PKN1 (0.77) | DHODHPARP1 | |
| SCHEMBL1298127 | 0.70 | PARP1 (0.73) | DHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622893-A1 | NEW ALICYCLIC-AMINE-SUBSTITUTED 4-CARBOXAMIDO-BENZIMIDAZOLES AS PARP-INHIBITORS AND ANTIOXIDANTS | Hideg, Kalman (HU) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004096793-A1 | NEW ALICYCLIC-AMINE-SUBSTITUTED 4-CARBOXAMIDO-BENZIMIDAZOLES AS PARP-INHIBITORS AND ANTIOXIDANTS | HIDEG KALMAN (HU) | 2004-11-11 | — | — | WO | disclosed |