Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.53 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1624384 | 0.91 | PTGER4 (0.52) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL6897561 | 0.82 | PTGER4 (0.49) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1624676 | 0.81 | PTGER4 (0.70) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1626699 | 0.80 | PTGER4 (0.64) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1625565 | 0.80 | PTGER4 (0.64) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1625246 | 0.79 | PTGER4 (0.65) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1625577 | 0.79 | PTGER4 (0.53) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1625122 | 0.79 | PTGER4 (0.64) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1626191 | 0.79 | PTGER4 (0.64) | PTGER4CA12CA1CA2CA9 | |
| SCHEMBL1625573 | 0.79 | PTGER4 (0.64) | PTGER4CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-B1 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMA (JP) | 2006-03-15 | — | — | EP | disclosed |