Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563209 | 0.89 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL3567431 | 0.89 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL3578115 | 0.89 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL3579225 | 0.89 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL3570956 | 0.89 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL3567442 | 0.89 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL3564579 | 0.78 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL3575534 | 0.78 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL3569834 | 0.78 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL3568294 | 0.78 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537114-B1 | ORGANIC COMPOUNDS AS AGENTS FOR THE TREATMENT OF ALDOSTERONE MEDIATED CONDITIONS | NOVARTIS AG (CH) | 2006-08-09 | — | — | EP | claimed |