Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5911726 | 1.00 | KMT2A (0.62) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL11603161 | 0.98 | KMT2A (0.63) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL20604382 | 0.91 | KMT2A (0.62) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL20604383 | 0.91 | KMT2A (0.62) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL477599 | 0.88 | SMN1; SMN2 (0.62) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL30863337 | 0.88 | KMT2A (0.61) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL23923495 | 0.87 | KMT2A (0.61) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL4162550 | 0.87 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL12221485 | 0.87 | KMT2A (0.61) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 | |
| SCHEMBL31748975 | 0.87 | KMT2A (0.61) | KMT2ASMN1; SMN2MEN1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1676635-A2 | Immobilisable ligands derived from ethylenediamine | Johnson Matthey PLC (GB) | 2006-07-05 | — | — | EP | disclosed |
| EP-1545772-A2 | NITROGEN-CONTAINING LIGANDS | Johnson Matthey PLC (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014551-A2 | IMMOBILISED LIGANDS DERIVED FROM ETHYLENEDIAMINE | JOHNSON MATTHEY PLC (GB) | 2004-02-19 | — | — | WO | disclosed |
| US-4087463-A | COBALT CARBONYL CATALYST | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |