SCHEMBL5772100

SCHEMBL5772100

Cc1nc(N2CC=CC2)c2[nH]c(-c3cccc(C(F)(F)F)c3)cc2n1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7190362 0.98 NPY5R (0.68) NPY5R
SCHEMBL5775210 0.89 NPY5R (0.78) NPY5R
Hydrochloric Acid SCHEMBL5772592 0.87 NPY5R (0.76) NPY5R
SCHEMBL5772015 0.83 NPY5R (0.76) NPY5R
SCHEMBL5774435 0.81 NPY5R (0.48) NPY5R
Hydrochloric Acid SCHEMBL5777025 0.81 NPY5R (0.72) NPY5R
SCHEMBL5773675 0.80 NPY5R (0.79) NPY5R
SCHEMBL5772065 0.80 NPY5R (0.50) NPY5R
Hydrochloric Acid SCHEMBL5773418 0.78 NPY5R (0.76) NPY5R
SCHEMBL5772796 0.78 NPY5R (0.72) NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054887-B1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS AMGEN INC (US) 2006-04-12 EP claimed