⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364899 | 0.84 | — | — | |
| SCHEMBL14212306 | 0.84 | KDM4E (0.46) | — | |
| SCHEMBL3148774 | 0.84 | TSHR (0.50) | — | |
| SCHEMBL30570 | 0.82 | — | — | |
| SCHEMBL15453228 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL393611 | 0.82 | — | — | |
| SCHEMBL9122292 | 0.82 | — | — | |
| SCHEMBL183408 | 0.82 | — | — | |
| SCHEMBL5000082 | 0.82 | — | — | |
| SCHEMBL10481674 | 0.80 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002341-A1 | GENETICALLY-ENCODED MACROCYCLIC PEPTIDE LIBRARIES BEARING A PHARMACOPHORE | 48Hour Discovery Inc. (CA) | 2022-01-06 | — | — | US | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| US-20250382725-A1 | GENETICALLY-ENCODED MACROCYCLIC PEPTIDE LIBRARIES BEARING A PHARMACOPHORE | 48HOUR DISCOVERY INC (CA) | 2025-12-18 | — | — | US | disclosed |
| US-12416101-B2 | Genetically-encoded macrocyclic peptide libraries bearing a pharmacophore | 48Hour Discovery Inc. (CA) | 2025-09-16 | — | — | US | disclosed |
| CN-118978498-B | Preparation method of 5-hydroxymethyl tetrahydrofuran-3-alcohol | 浙江雅辰药物科技股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-118978498-A | Preparation method of 5-hydroxymethyl tetrahydrofuran-3-alcohol | 浙江雅辰药物科技股份有限公司 | 2024-11-19 | — | — | CN | disclosed |
| WO-2023164777-A1 | GUCY2C-TARGETED RADIOPHARMACEUTICALS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023164777-A1 | GUCY2C-TARGETED RADIOPHARMACEUTICALS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2023-09-07 | — | — | WO | disclosed |
| US-20220002341-A1 | GENETICALLY-ENCODED MACROCYCLIC PEPTIDE LIBRARIES BEARING A PHARMACOPHORE | 48Hour Discovery Inc. (CA) | 2022-01-06 | — | — | US | disclosed |
| US-20220002341-A1 | GENETICALLY-ENCODED MACROCYCLIC PEPTIDE LIBRARIES BEARING A PHARMACOPHORE | 48Hour Discovery Inc. (CA) | 2022-01-06 | — | — | US | disclosed |
| EP-3887387-A1 | GENETICALLY-ENCODED MACROCYCLIC PEPTIDE LIBRARIES BEARING A PHARMACOPHORE | The Governors of the University of Alberta (CA) | 2021-10-06 | — | — | EP | disclosed |
| EP-1358190-A1 | AMORPHOUS ORGANIC 1,3,2-DIOXABORINE LUMINOPHORES, METHOD FOR THE PRODUCTION AND USE THEREOF | Siemens Aktiengesellschaft (DE) | 2003-11-05 | — | — | EP | disclosed |
| US-6610875-B1 | Forming bidentate ligands ofr assymetric catalysts; bromina-ting diaryldiol; esterifying with sulfonic acid; substituting cyano for bromine groups; coupling with a dicyclophosphine | RHODIA CHIMIE (FR) | 2003-08-26 | — | — | US | disclosed |
| EP-1161481-B1 | OPTICALLY ACTIVE LINEAR POLYMER USED AS LIGAND IN THE PREPARATION OF METALLIC COMPLEXES DESIGNED FOR ASYMMETRIC CATALYSIS | RHODIA CHIMIE SA (FR) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002064600-A1 | AMORPHOUS ORGANIC 1,3,2-DIOXABORINE LUMINOPHORES, METHOD FOR THE PRODUCTION AND USE THEREOF | SIEMENS AKTIENGESELLSCHAFT (DE) | 2002-08-22 | — | — | WO | disclosed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | disclosed |
| WO-2002021611-A1 | NOVEL PHOTOSTRUCTURABLE ORGANIC SEMICONDUCTOR MATERIALS | SIEMENS AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| US-6166257-A | METAL COMPLEX OF AN OPTICALLY ACTIVE BIS(1-PHOSPHA-2,3-DIPHENYL-4,5-DIMETHYLNORBORNADIENE) | RHODIA CHIMIE (FR) | 2000-12-26 | — | — | US | disclosed |
| EP-0297752-B1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALCOHOL | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4916252-A | OPTICALLY ACTIVE PHOSPHINE-RUTHENIUM HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |