Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5719191 | 0.89 | DPP4 (0.41) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5791981 | 0.87 | DPP4 (0.44) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5719200 | 0.87 | DPP4 (0.40) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL6379680 | 0.82 | DPP4 (0.46) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5718955 | 0.82 | DPP4 (0.38) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5772367 | 0.82 | DPP4 (0.45) | DPP4MEN1KMT2AL3MBTL1GAA | |
| Trifluoroacetic Acid SCHEMBL5718976 | 0.81 | DPP4 (0.44) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5718965 | 0.80 | DPP4 (0.47) | DPP4MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5719535 | 0.79 | DPP4 (0.40) | DPP4MEN1KMT2AL3MBTL1GAA | |
| Trifluoroacetic Acid SCHEMBL5718959 | 0.78 | DPP4 (0.50) | DPP4MEN1KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | DPP4 1/4885MEN1 1858/4885KMT2A 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.