Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772678 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| SCHEMBL1566108 | 0.91 | KMT2A (0.60) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| SCHEMBL19415790 | 0.90 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| SCHEMBL12446273 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| SCHEMBL2749197 | 0.87 | KMT2A (0.63) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| SCHEMBL28115743 | 0.87 | KMT2A (0.67) | SMN1; SMN2KMT2AMAOBSGMS2CYP4F2 | |
| SCHEMBL28115744 | 0.87 | KMT2A (0.67) | SMN1; SMN2KMT2AMAOBSGMS2CYP4F2 | |
| Hydrochloric Acid SCHEMBL30662874 | 0.85 | KMT2A (0.62) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| Hydrochloric Acid SCHEMBL9461016 | 0.85 | KMT2A (0.62) | SMN1; SMN2KMT2AMAOBSGMS2BCHE | |
| Hydrochloric Acid SCHEMBL26610965 | 0.85 | KMT2A (0.62) | SMN1; SMN2KMT2AMAOBSGMS2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1676635-A2 | Immobilisable ligands derived from ethylenediamine | Johnson Matthey PLC (GB) | 2006-07-05 | — | — | EP | disclosed |
| US-20060135355-A1 | Nitrogen-containing ligands | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2006-06-22 | — | — | US | disclosed |
| EP-1545772-A2 | NITROGEN-CONTAINING LIGANDS | Johnson Matthey PLC (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014551-A2 | IMMOBILISED LIGANDS DERIVED FROM ETHYLENEDIAMINE | JOHNSON MATTHEY PLC (GB) | 2004-02-19 | — | — | WO | disclosed |