Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772718 | 1.00 | DPP4 (0.52) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL8491789 | 0.80 | SCN9A (0.43) | — | |
| SCHEMBL4917495 | 0.80 | SCN9A (0.43) | — | |
| SCHEMBL4913509 | 0.80 | DPP4 (0.53) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL4913502 | 0.80 | DPP4 (0.53) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL8293131 | 0.79 | DPP4 (0.51) | DPP4DPP7DPP8 | |
| SCHEMBL8288194 | 0.78 | DPP4 (0.52) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL8474193 | 0.77 | DPP4 (0.55) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL8474122 | 0.77 | DPP4 (0.55) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL14007013 | 0.76 | DPP4 (0.52) | DPP4DPP7DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702916-A1 | DPP-IV inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-09-20 | — | — | EP | disclosed |