Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 10/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767853 | 0.93 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5770614 | 0.90 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5769740 | 0.89 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5771427 | 0.89 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5772048 | 0.89 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5769065 | 0.87 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5770910 | 0.87 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5768797 | 0.86 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5769729 | 0.86 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL6805067 | 0.86 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |
| US-6989395-B2 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2006-01-24 | — | — | US | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |