Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886853 | 0.78 | F2 (0.44) | KDM4ECYP2C9 | |
| SCHEMBL5773458 | 0.77 | F2 (0.38) | KDM4ECYP2C9 | |
| SCHEMBL3890749 | 0.76 | F2 (0.32) | KDM4ECYP2C9 | |
| SCHEMBL13792116 | 0.75 | F2 (0.44) | — | |
| SCHEMBL5771914 | 0.70 | F2 (0.43) | — | |
| SCHEMBL3888694 | 0.69 | KDM4E (0.45) | KDM4ECYP2C9 | |
| SCHEMBL5774527 | 0.64 | F2 (0.53) | — | |
| SCHEMBL31682816 | 0.63 | KDM4E (0.40) | KDM4EAR | |
| SCHEMBL4332770 | 0.61 | RXFP1 (0.39) | KDM4EAR | |
| SCHEMBL3888182 | 0.60 | F2 (0.66) | KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613319-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091613-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |