Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772622 | 0.89 | NPY5R (0.81) | NPY5R | |
| SCHEMBL5771890 | 0.89 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5773341 | 0.89 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5774658 | 0.88 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5770259 | 0.88 | NPY5R (1.00) | NPY5R | |
| Hydrochloric Acid SCHEMBL5773697 | 0.87 | NPY5R (0.78) | NPY5R | |
| SCHEMBL5774811 | 0.86 | NPY5R (1.00) | NPY5R | |
| Hydrochloric Acid SCHEMBL5775494 | 0.86 | NPY5R (0.97) | NPY5R | |
| Hydrochloric Acid SCHEMBL5776797 | 0.86 | NPY5R (0.95) | NPY5R | |
| Hydrochloric Acid SCHEMBL5777284 | 0.86 | NPY5R (0.95) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-6583154-B1 | Neuropeptide Y antagonist; pyrrolo-(3,2-b)pyridines and pyrrolo-(3,2-d)pyrimidines | AMGEN INC. | 2003-06-24 | — | — | US | disclosed |
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | disclosed |