Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626683 | 0.97 | PTGER4 (0.57) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1625224 | 0.90 | PTGER4 (0.59) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1624408 | 0.87 | PTGER4 (0.62) | PTGER4CA2CA9CA12CA1 | |
| Formic Acid SCHEMBL1624052 | 0.87 | PTGER4 (0.58) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1625673 | 0.85 | PTGER4 (0.62) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1623404 | 0.85 | PTGER4 (0.66) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1625334 | 0.85 | PTGER4 (0.57) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1624990 | 0.85 | PTGER4 (0.61) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1626529 | 0.85 | PTGER4 (0.61) | PTGER4CA2CA9CA12CA1 | |
| SCHEMBL1625850 | 0.85 | PTGER4 (0.65) | PTGER4CA2CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-B1 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMA (JP) | 2006-03-15 | — | — | EP | disclosed |