Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774788 | 0.88 | NPY5R (0.78) | NPY5RNCF1 | |
| SCHEMBL5774658 | 0.80 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5770259 | 0.80 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5771574 | 0.79 | NPY5R (0.65) | NPY5R | |
| Hydrochloric Acid SCHEMBL5775494 | 0.79 | NPY5R (0.97) | NPY5R | |
| Hydrochloric Acid SCHEMBL5776809 | 0.78 | NPY5R (0.64) | NPY5R | |
| SCHEMBL5771890 | 0.78 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5773254 | 0.78 | NPY5R (1.00) | NPY5R | |
| Hydrochloric Acid SCHEMBL5775447 | 0.78 | NPY5R (0.95) | NPY5R | |
| SCHEMBL7981527 | 0.77 | NPY5R (0.64) | NPY5RNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-6583154-B1 | Neuropeptide Y antagonist; pyrrolo-(3,2-b)pyridines and pyrrolo-(3,2-d)pyrimidines | AMGEN INC. | 2003-06-24 | — | — | US | disclosed |
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | disclosed |
| EP-1054887-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040091-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 1999-08-12 | — | — | WO | disclosed |