Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 14/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774598 | 1.00 | KCNH2 (0.48) | KCNH2SLC2A1LTA4H | |
| SCHEMBL5726860 | 0.78 | SLC2A1 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL4275516 | 0.72 | SLC2A1 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL4275507 | 0.72 | SLC2A1 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL4275515 | 0.72 | SLC2A1 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL3250180 | 0.71 | SLC2A1 (0.42) | KCNH2SLC2A1 | |
| SCHEMBL3250184 | 0.71 | SLC2A1 (0.42) | KCNH2SLC2A1 | |
| SCHEMBL5796470 | 0.70 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL5727277 | 0.67 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL5728549 | 0.67 | SLC2A1 (0.61) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | disclosed |