⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513941 | 1.00 | — | — | |
| SCHEMBL5771584 | 0.85 | — | — | |
| SCHEMBL7497777 | 0.84 | — | — | |
| SCHEMBL5771505 | 0.83 | — | — | |
| SCHEMBL7498780 | 0.83 | — | — | |
| SCHEMBL7550722 | 0.77 | — | — | |
| SCHEMBL6936809 | 0.77 | — | — | |
| SCHEMBL6937086 | 0.77 | — | — | |
| SCHEMBL6940162 | 0.77 | — | — | |
| SCHEMBL7503301 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203767-B1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER LAMBERT CO (US) | 2006-01-04 | — | — | EP | claimed |
| EP-1203767-A1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | claimed |
| EP-0684945-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-06 | — | — | EP | claimed |
| WO-1994019330-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-09-01 | — | — | WO | claimed |