Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268016 | 0.89 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5776339 | 0.88 | HTT (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3272685 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL3268699 | 0.80 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL3268694 | 0.80 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL3267117 | 0.78 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL3267112 | 0.78 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13307095 | 0.71 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6186637 | 0.70 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4492237 | 0.69 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735302-A1 | 4-AMINO-PIPERIDINE DERIVATIVES AS MONOAMINE UPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092885-A1 | 4-AMINO-PIPERIDINE DERIVATIVES AS MONOAMINE UPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-06 | — | — | WO | disclosed |