Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.68 |
| ▸ | CA6 | P23280 | 5/20 | 0.68 |
| ▸ | CA7 | P43166 | 5/20 | 0.68 |
| ▸ | CA9 | Q16790 | 5/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.68 |
| ▸ | CA2 | P00918 | 4/20 | 0.68 |
| ▸ | CA4 | P22748 | 4/20 | 0.68 |
| ▸ | CA5A | P35218 | 4/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | CA3 | P07451 | 3/20 | 0.68 |
| ▸ | F13A1 | P00488 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | THPO | P40225 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934861 | 0.97 | CA12 (0.65) | CA12CA6CA7CA9CA14 | |
| SCHEMBL12819203 | 0.92 | CA12 (0.65) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5497916 | 0.92 | — | — | |
| SCHEMBL10424375 | 0.89 | CA12 (0.72) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8309907 | 0.88 | — | — | |
| SCHEMBL732232 | 0.85 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| SCHEMBL448382 | 0.85 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| SCHEMBL138047 | 0.85 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| SCHEMBL323273 | 0.85 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| SCHEMBL322518 | 0.85 | CA12 (0.93) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631570-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Abbott Laboratories (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2004083207-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ABBOTT LABORATORIES (US) | 2004-09-30 | — | — | WO | claimed |
| EP-0637243-B1 | NOVEL AMINOSTEROL ANTIBIOTIC | PHILADELPHIA CHILDREN HOSPITAL (US) | 1997-04-23 | — | — | EP | claimed |
| EP-1631570-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Abbott Laboratories (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004083207-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ABBOTT LABORATORIES (US) | 2004-09-30 | — | — | WO | disclosed |
| US-5763430-A | ANTIGROWTH AGENTS OF VIRUS | MAGAININ PHARMACEUTICALS INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0637243-B1 | NOVEL AMINOSTEROL ANTIBIOTIC | PHILADELPHIA CHILDREN HOSPITAL (US) | 1997-04-23 | — | — | EP | disclosed |