Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775961 | 0.74 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5771207 | 0.74 | NPY5R (0.70) | NPY5R | |
| SCHEMBL6215999 | 0.74 | NPY5R (0.70) | NPY5R | |
| SCHEMBL5774510 | 0.73 | NPY5R (0.76) | NPY5R | |
| SCHEMBL7184161 | 0.73 | NPY5R (0.63) | NPY5R | |
| Hydrochloric Acid SCHEMBL5776730 | 0.73 | NPY5R (0.69) | NPY5R | |
| SCHEMBL5777041 | 0.73 | NPY5R (0.54) | NPY5RPFKFB3 | |
| SCHEMBL8115272 | 0.72 | NPY5R (0.73) | NPY5R | |
| Hydrochloric Acid SCHEMBL7189701 | 0.71 | NPY5R (0.97) | NPY5R | |
| Hydrochloric Acid SCHEMBL7184436 | 0.71 | NPY5R (0.72) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-6583154-B1 | Neuropeptide Y antagonist; pyrrolo-(3,2-b)pyridines and pyrrolo-(3,2-d)pyrimidines | AMGEN INC. | 2003-06-24 | — | — | US | disclosed |
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | disclosed |