Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 16/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774686 | 0.92 | BRAF (0.42) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL5776870 | 0.90 | MAPK14 (0.46) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL13757124 | 0.89 | BRAF (0.44) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL5808806 | 0.88 | MAPK14 (0.41) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL5779482 | 0.88 | BRAF (0.47) | BRAF | |
| SCHEMBL5777714 | 0.88 | MAPK14 (0.44) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL5812004 | 0.88 | BRAF (0.45) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL5778571 | 0.87 | MAPK14 (0.41) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL5779620 | 0.86 | BRAF (0.45) | BRAF | |
| SCHEMBL5778687 | 0.85 | MAPK14 (0.43) | BRAFMAPK14LYNMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567507-B1 | 1,2,3- TRIAZOLE AMIDE DERIVATIVES AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2006-06-14 | — | — | EP | claimed |