Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2554663 | 0.98 | MAPT (0.71) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL28788564 | 0.85 | POLB (1.00) | MAPTKDM4ENPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL6697133 | 0.83 | POLB (0.96) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL17188149 | 0.82 | EPHX1 (0.53) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL12998745 | 0.82 | TDP1 (0.69) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL2345038 | 0.81 | SMN1; SMN2 (0.57) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL4157373 | 0.80 | MAPT (0.53) | MAPTKDM4ENPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL17362383 | 0.80 | TDP1 (0.67) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL1483327 | 0.80 | IDO1 (0.66) | MAPTKDM4ENPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL17825653 | 0.79 | MAPT (0.51) | MAPTKDM4ENPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250383357-A1 | NOVEL FLUORESCENT DYES AND POLYMERS FROM DIHYDROPHENANTHRENE DERIVATIVES | BECKMAN COULTER INC (US) | 2025-12-18 | — | — | US | disclosed |
| CN-119630747-A | Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives | 贝克曼库尔特有限公司 | 2025-03-14 | — | — | CN | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| US-9969724-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170129880-A1 | FACTOR IXa INHIBITORS | MERCK SHARP & DOHME LLC | 2017-05-11 | — | — | US | disclosed |
| EP-3131897-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015160636-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-9024041-B2 | P38 MAP kinase inhibitors | RESPIVERT LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| US-20130040962-A1 | P38 MAP Kinase Inhibitors | RESPIVERT LTD (GB) | 2013-02-14 | — | — | US | disclosed |
| WO-2011124930-A1 | P38 MAP KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2011-10-13 | — | — | WO | disclosed |
| EP-1409485-B1 | IMMUNOMODULATING COMPOUNDS | ACTIVE BIOTECH AB (SE) | 2006-04-26 | — | — | EP | disclosed |
| CN-1249063-C | Novel Immunomodulatory Compounds | ACTIVE BIOTECH AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1522254-A | Novel Immunomodulatory Compounds | ��Ծ���＼���ɷݹ�˾ | 2004-08-18 | — | — | CN | disclosed |
| EP-1409485-A1 | NOVEL IMMUNOMODULATING COMPOUNDS | Active Biotech AB (SE) | 2004-04-21 | — | — | EP | disclosed |
| US-6642249-B2 | 3-Oxo-pyrazolo(4,3-c) -quinolin-2-yl, -thiochroman-2-yl, or -chromen-2-yl derivatives; CD80 antagonists | ACTIVE BIOTECH AB (SE) | 2003-11-04 | — | — | US | disclosed |
| US-20030022913-A1 | Novel immunomodulating compounds | ACTIVE BIOTECH AB (SE) | 2003-01-30 | — | — | US | disclosed |
| WO-2003004495-A1 | NOVEL IMMUNOMODULATING COMPOUNDS | ACTIVE BIOTECH AB (SE) | 2003-01-16 | — | — | WO | disclosed |
| CN-1072210-C | 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors | SANOFI SYNTHELABO (FR) | 2001-10-03 | — | — | CN | disclosed |
| US-4045169-A | FLUORESCENT DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |
| US-3957815-A | 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129880-A1 | FACTOR IXa INHIBITORS | F9, F12, TFPI | MAPT 3891/4885KDM4E 837/4885NPC1 2231/4885 |
| US-20030022913-A1 | Novel immunomodulating compounds | CD40, ICOS, CD40LG | MAPT 3867/4885KDM4E 2144/4885NPC1 3082/4885 |
| US-20130040962-A1 | P38 MAP Kinase Inhibitors | MAPK15, MAPK1, MAP3K15 | MAPT 890/4885KDM4E 3646/4885NPC1 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.