Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 15/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782569 | 0.96 | FGFR1 (0.61) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL5780723 | 0.86 | FGFR1 (0.61) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL2652306 | 0.86 | FGFR1 (0.48) | FGFR1HPGDALDH1A1NPC1GLA | |
| SCHEMBL5780808 | 0.85 | FGFR1 (0.60) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL5781826 | 0.85 | HPGD (0.55) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL5781457 | 0.84 | FGFR1 (0.65) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL5778137 | 0.84 | FGFR1 (0.62) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL5780132 | 0.84 | FGFR1 (0.59) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL5781363 | 0.84 | FGFR1 (0.54) | FGFR1HPGDALDH1A1LMNANPC1 | |
| SCHEMBL2652333 | 0.84 | FGFR1 (0.54) | FGFR1HPGDALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | claimed |