Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780455 | 0.90 | CNR2 (0.73) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5778081 | 0.89 | CNR2 (0.75) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5780667 | 0.88 | CNR2 (0.81) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5777944 | 0.87 | CNR2 (0.75) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5079081 | 0.86 | CNR2 (1.00) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5780836 | 0.85 | CNR2 (0.79) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5078986 | 0.85 | CNR2 (0.85) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5779399 | 0.85 | CNR2 (0.75) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5777464 | 0.85 | CNR2 (0.75) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5079600 | 0.84 | CNR2 (1.00) | CNR2CYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736470-A2 | Pyrimidine derivatives as CB2 cannabinoid receptor modulators | GLAXO GROUP LIMITED (GB) | 2006-12-27 | — | — | EP | disclosed |