Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 0.77 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776492 | 0.89 | TBXA2R (0.79) | TBXA2RPTGDR | |
| SCHEMBL5777618 | 0.87 | TBXA2R (0.79) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5773893 | 0.87 | TBXA2R (1.00) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL6738757 | 0.86 | TBXA2R (0.78) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5834981 | 0.85 | TBXA2R (0.56) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5778629 | 0.85 | TBXA2R (0.76) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5774522 | 0.84 | TBXA2R (0.75) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5774620 | 0.84 | TBXA2R (0.75) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5774988 | 0.82 | TBXA2R (0.67) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL5777761 | 0.81 | TBXA2R (0.89) | TBXA2RPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |