Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509197 | 0.88 | — | — | |
| SCHEMBL9939811 | 0.79 | — | — | |
| SCHEMBL6320194 | 0.75 | GBA1 (0.31) | GBA1 | |
| Hydrochloric Acid SCHEMBL7291186 | 0.73 | GBA1 (0.37) | GBA1 | |
| SCHEMBL23265771 | 0.71 | — | — | |
| SCHEMBL2077537 | 0.71 | — | — | |
| SCHEMBL20685187 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL23245470 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL23245472 | 0.69 | — | — | |
| SCHEMBL23889199 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432702-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS RAF INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2006-08-16 | — | — | EP | disclosed |
| EP-0422846-A2 | Aroyl-ureas | JOHN WYETH & BROTHER LIMITED (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0289170-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-11-02 | — | — | EP | disclosed |