Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.56 |
| ▸ | FNTB | P49356 | 9/20 | 0.56 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPR1 | P16066 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783326 | 0.87 | FNTA (0.58) | FNTAFNTBPGGT1BNPR1 | |
| SCHEMBL5781151 | 0.85 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL5780208 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL5782193 | 0.85 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL5782042 | 0.85 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL5784774 | 0.83 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL5782628 | 0.83 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL5779856 | 0.82 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL5783128 | 0.81 | FNTA (0.66) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL5780158 | 0.79 | FNTA (0.64) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322635-B1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2006-03-22 | — | — | EP | claimed |