Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773618 | 0.87 | TBXA2R (0.71) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5776057 | 0.77 | TBXA2R (0.81) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5776506 | 0.77 | TBXA2R (0.51) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5776865 | 0.75 | TBXA2R (0.59) | TBXA2RPTGDR2PTGDR | |
| SCHEMBL5777316 | 0.69 | TBXA2R (1.00) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5840675 | 0.69 | TBXA2R (1.00) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5800203 | 0.68 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5777289 | 0.68 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5777305 | 0.68 | TBXA2R (1.00) | TBXA2RPTGDR2PTGDRPDE2A | |
| SCHEMBL5776580 | 0.68 | TBXA2R (0.84) | TBXA2RPTGDR2PTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |