Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 19/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809161 | 0.94 | BRAF (0.46) | BRAF | |
| SCHEMBL5813134 | 0.94 | BRAF (0.46) | BRAF | |
| SCHEMBL5808598 | 0.93 | BRAF (0.48) | BRAF | |
| SCHEMBL5813856 | 0.92 | BRAF (0.52) | BRAF | |
| SCHEMBL14602785 | 0.90 | BRAF (0.55) | BRAFSRCSYKGSK3A | |
| SCHEMBL5779460 | 0.88 | BRAF (0.47) | BRAF | |
| SCHEMBL5809533 | 0.88 | BRAF (0.47) | BRAF | |
| SCHEMBL5780116 | 0.87 | BRAF (0.48) | BRAFGSK3A | |
| SCHEMBL5779482 | 0.87 | BRAF (0.47) | BRAF | |
| SCHEMBL5778311 | 0.87 | BRAF (0.47) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567507-B1 | 1,2,3- TRIAZOLE AMIDE DERIVATIVES AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2006-06-14 | — | — | EP | claimed |