SCHEMBL5779205

SCHEMBL5779205

NCC1CCN(CCc2ccccc2)C1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 2/20 0.64
ACHE P22303 1/20 0.57
CARM1 Q86X55 2/20 0.54
PRMT6 Q96LA8 2/20 0.54
PRMT3 O60678 1/20 0.54
PRMT1 Q99873 1/20 0.54
PRMT8 Q9NR22 1/20 0.54
SLC6A3 Q01959 1/20 0.51
SIGMAR1 Q99720 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3594852 0.90 CCR3 (0.73) CCR3ACHECARM1PRMT6PRMT3
Hydrochloric Acid SCHEMBL23124024 0.89 CCR3 (0.71) CCR3ACHECARM1PRMT6PRMT3
SCHEMBL10447127 0.84 CCR3 (0.65) CCR3ACHECARM1PRMT6PRMT3
SCHEMBL843343 0.84 CCR3 (0.64) CCR3ACHESLC6A3
SCHEMBL11023730 0.84 CCR3 (0.64) CCR3ACHECARM1PRMT6SLC6A3
SCHEMBL6172031 0.84 CCR3 (0.64) CCR3ACHECARM1PRMT6SLC6A3
SCHEMBL5069409 0.84 CCR3 (0.64) CCR3ACHESLC6A3
SCHEMBL7465330 0.84 CCR3 (0.64) CCR3ACHESLC6A3
SCHEMBL843329 0.84 CCR3 (0.64) CCR3ACHECARM1PRMT6SLC6A3
SCHEMBL242758 0.83 CCR3 (0.62) CCR3ACHECARM1PRMT6PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687296-A1 ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES Warner-Lambert Company LLC (US) 2006-08-09 EP disclosed
WO-2005049602-A1 QUINOLONE ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2005-06-02 WO disclosed
WO-2005049605-A1 ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES WARNER-LAMBERT COMPANY LLC (US) 2005-06-02 WO disclosed