Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.49 |
| ▸ | CDK1 | P06493 | 3/20 | 0.49 |
| ▸ | SMG1 | Q96Q15 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | BCR | P11274 | 2/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632285 | 0.83 | CDK2 (0.59) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL14527056 | 0.83 | SMG1 (0.53) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL5631117 | 0.80 | CDK2 (0.53) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL5629944 | 0.80 | CDK2 (0.53) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL5630483 | 0.78 | CDK2 (0.54) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL5629931 | 0.77 | SMG1 (0.56) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL5779080 | 0.76 | CDK2 (0.54) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL14527047 | 0.74 | CDK2 (0.52) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL6109242 | 0.73 | CDK2 (0.62) | CDK2CDK1SMG1MAPTABL1 | |
| SCHEMBL5628934 | 0.73 | CDK2 (0.55) | CDK2CDK1SMG1MAPTABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471786-B1 | MICROBIOCIDAL N-PHENYL-N- 4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL|-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-12-27 | — | — | EP | disclosed |
| EP-1471786-A1 | MICROBIOCIDAL N-PHENYL-N- 4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | Syngenta Participations AG (CH) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003047347-A1 | MICROBIOCIDAL N-PHENYL-N-[4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-12 | — | — | WO | disclosed |