⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094480 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL3055820 | 0.67 | — | — | |
| SCHEMBL2781581 | 0.64 | — | — | |
| SCHEMBL19080490 | 0.64 | KDM4E (0.39) | — | |
| SCHEMBL4724871 | 0.64 | — | — | |
| SCHEMBL19080649 | 0.62 | KDM4E (0.65) | — | |
| SCHEMBL18756076 | 0.62 | KDM4E (0.65) | — | |
| SCHEMBL4723751 | 0.61 | EPHX1 (0.33) | — | |
| SCHEMBL8040570 | 0.60 | KDM4E (0.39) | — | |
| SCHEMBL8037123 | 0.60 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631570-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Abbott Laboratories (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2004083207-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ABBOTT LABORATORIES (US) | 2004-09-30 | — | — | WO | claimed |