Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090493 | 0.88 | PIM2 (0.37) | PPARDPPARAIDH1 | |
| SCHEMBL578241 | 0.88 | PIM2 (0.37) | PPARDPPARAIDH1 | |
| SCHEMBL578223 | 0.78 | PIM2 (0.41) | PPARDPPARA | |
| SCHEMBL13090476 | 0.78 | PIM2 (0.41) | PPARDPPARA | |
| SCHEMBL578075 | 0.76 | PIK3CD (0.34) | PPARDPPARAIDH1 | |
| SCHEMBL16264825 | 0.73 | PIM1 (0.40) | PPARDPPARA | |
| SCHEMBL577800 | 0.72 | PDE4B (0.36) | PPARDPPARAIDH1 | |
| SCHEMBL13090489 | 0.71 | TP53 (0.38) | PPARDPPARA | |
| SCHEMBL591780 | 0.69 | EGFR (0.34) | PPARDPPARA | |
| SCHEMBL13090495 | 0.69 | EGFR (0.34) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417134-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |