Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.78 |
| ▸ | LCK | P06239 | 1/20 | 0.78 |
| ▸ | FYN | P06241 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1844528 | 1.00 | — | — | |
| Acetic Acid SCHEMBL11766343 | 1.00 | FFAR3 (0.78) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL20137312 | 0.95 | FFAR3 (0.70) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL4346329 | 0.95 | FFAR3 (0.70) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL4217512 | 0.94 | FFAR3 (0.88) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL8182975 | 0.94 | FFAR3 (0.88) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL2402511 | 0.94 | — | — | |
| Acetic Acid SCHEMBL21084343 | 0.94 | FFAR3 (0.88) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL586755 | 0.94 | — | — | |
| Acetic Acid SCHEMBL18753 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113860791-B | Quick response type concrete self-repairing capsule and preparation method thereof | 东南大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113860791-A | Quick response type concrete self-repairing capsule and preparation method thereof | 东南大学 | 2021-12-31 | — | — | CN | disclosed |
| US-20210161827-A1 | TASTE-MASKED PHARMACEUTICAL COMPOSITIONS WITH GASTROSOLUBLE PORE-FORMERS | ADARE PHARMACEUTICALS, INC. | 2021-06-03 | — | — | US | disclosed |
| US-10952971-B2 | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers | ADARE PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-10471017-B2 | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers | ADARE PHARMACEUTICALS, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190290591-A1 | TASTE-MASKED PHARMACEUTICAL COMPOSITIONS WITH GASTROSOLUBLE PORE-FORMERS | TEAL MIDCO HOLDINGS, L.P. | 2019-09-26 | — | — | US | disclosed |
| US-20170105942-A1 | TASTE-MASKED PHARMACEUTICAL COMPOSITIONS WITH GASTROSOLUBLE PORE-FORMERS | ADARE PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | US | disclosed |
| EP-1802285-B1 | TASTE-MASKED PHARMACEUTICAL COMPOSITIONS WITH GASTROSOLUBLE PORE-FORMERS | APTALIS PHARMATECH INC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2417969-A1 | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers | Aptalis Pharmatech, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1802285-A2 | TASTE-MASKED PHARMACEUTICAL COMPOSITIONS WITH GASTROSOLUBLE PORE-FORMERS | Eurand Pharmaceuticals Ltd (IE) | 2007-07-04 | — | — | EP | disclosed |
| US-20060105039-A1 | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers | ADARE PHARMACEUTICALS, INC. | 2006-05-18 | — | — | US | disclosed |
| WO-2006047493-A2 | TASTE-MASKED PHARMACEUTICAL COMPOSITIONS WITH GASTROSOLUBLE PORE-FORMERS | EURAND PHARMACEUTICALS LIMITED (IE) | 2006-05-04 | — | — | WO | disclosed |