Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.49 |
| ▸ | ACP1 | P24666 | 7/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.47 |
| ▸ | PTPRF | P10586 | 2/20 | 0.47 |
| ▸ | PTPRB | P23467 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782161 | 1.00 | KMT2A (0.55) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5464240 | 0.87 | MEN1 (0.61) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5464235 | 0.87 | MEN1 (0.61) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5470522 | 0.86 | PTPN1 (0.54) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5470519 | 0.86 | PTPN1 (0.54) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5468585 | 0.86 | MEN1 (0.59) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5468591 | 0.86 | MEN1 (0.59) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5462470 | 0.84 | PTPN1 (0.59) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5462464 | 0.84 | PTPN1 (0.59) | KMT2AMEN1NSD2HSP90AA1APOBEC3G | |
| SCHEMBL5472001 | 0.80 | MEN1 (0.69) | KMT2AMEN1NSD2HSP90AA1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |