Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | BAG3 | O95817 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783365 | 1.00 | MEN1 (0.72) | MEN1KMT2AL3MBTL1USP2ALDH1A1 | |
| SCHEMBL5459430 | 0.82 | PTPN1 (0.61) | MEN1KMT2APOLBKDR | |
| SCHEMBL5459436 | 0.82 | PTPN1 (0.61) | MEN1KMT2APOLBKDR | |
| SCHEMBL5460324 | 0.80 | MEN1 (0.65) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL5460326 | 0.80 | MEN1 (0.65) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29028344 | 0.80 | PTPN1 (0.72) | MEN1KMT2AL3MBTL1USP2ALDH1A1 | |
| SCHEMBL29028638 | 0.79 | MEN1 (0.70) | MEN1KMT2AL3MBTL1USP2ALDH1A1 | |
| SCHEMBL15682752 | 0.79 | MEN1 (0.78) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL29028351 | 0.79 | MEN1 (0.73) | MEN1KMT2AL3MBTL1USP2ALDH1A1 | |
| SCHEMBL29028359 | 0.79 | KMT2A (0.73) | MEN1KMT2AL3MBTL1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |