Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784839 | 0.95 | HPGD (0.34) | HPGDADORA2BALDH1A1MAPTCYP1A2 | |
| SCHEMBL5784542 | 0.90 | HPGD (0.39) | HPGDADORA2BALDH1A1MAPTCYP1A2 | |
| SCHEMBL5787931 | 0.90 | MAPT (0.35) | ADORA2BALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL5784707 | 0.88 | HPGD (0.38) | HPGDADORA2BALDH1A1MAPTCYP1A2 | |
| SCHEMBL5783826 | 0.88 | — | — | |
| SCHEMBL5788598 | 0.88 | KDM4E (0.33) | HPGDALDH1A1NPSR1KDM4EHSD17B10 | |
| SCHEMBL5784466 | 0.87 | PDE4B (0.35) | ADORA2BALDH1A1NPSR1GLAADORA2A | |
| SCHEMBL5783887 | 0.87 | NR1H4 (0.30) | — | |
| SCHEMBL5786901 | 0.87 | HPGD (0.35) | HPGDADORA2BALDH1A1MAPTCYP1A2 | |
| SCHEMBL5785742 | 0.86 | HPGD (0.36) | HPGDADORA2BALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |