Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 7/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 5/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931870 | 0.83 | MAPK14 (0.44) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1386590 | 0.80 | NPC1 (0.40) | CSNK1DCSNK1EMAPK14MAPK11KCNH2 | |
| SCHEMBL2932159 | 0.79 | ADORA2A (0.40) | CSNK1DCSNK1EMAPK14MAPK11KCNH2 | |
| SCHEMBL1386174 | 0.78 | GRM2 (0.41) | CSNK1DCSNK1EMAPK14MAPK11KCNH2 | |
| SCHEMBL1385787 | 0.78 | RIPK3 (0.48) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1384346 | 0.78 | MAPK14 (0.42) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL2927446 | 0.77 | MAPK14 (0.46) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1383998 | 0.76 | MAPK14 (0.47) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1384274 | 0.76 | MAPK14 (0.46) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1384099 | 0.76 | MAPK14 (0.41) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-A1 | PYRAZOLOPYRIDINE DERIVATES | J. Uriach y Compagnia S.A. (ES) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004076450-A1 | PYRAZOLOPYRIDINE DERIVATES | J. Uriach Y Compañia S.A. (ES) | 2004-09-10 | — | — | WO | disclosed |