Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784045 | 0.85 | PTPN1 (0.82) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL5784054 | 0.82 | PTPN1 (0.68) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL3053397 | 0.82 | KMT2A (0.60) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL13088584 | 0.81 | KMT2A (0.59) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL13088595 | 0.81 | KCNH2 (0.69) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL13088582 | 0.80 | KMT2A (0.58) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL3054924 | 0.80 | KMT2A (0.58) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL31337212 | 0.80 | PTPN1 (0.64) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL13088590 | 0.79 | KCNH2 (0.57) | PTPN1PTPN11KMT2AMEN1ALDH1A1 | |
| SCHEMBL3058933 | 0.79 | KMT2A (0.57) | PTPN1PTPN11KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723132-A1 | EP2 RECEPTOR AGONISTS | ASTERAND UK LIMITED (GB) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005080367-A1 | EP2 RECEPTOR AGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |