Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.54 |
| ▸ | FAP | Q12884 | 2/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 3/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129828 | 1.00 | DPP4 (0.66) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL2606781 | 1.00 | DPP4 (0.66) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL3129738 | 1.00 | DPP4 (0.66) | DPP4DPP7FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2107365 | 0.99 | DPP4 (0.65) | DPP4DPP7FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2107366 | 0.99 | DPP4 (0.65) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL2606751 | 0.92 | DPP4 (0.62) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4327505 | 0.92 | DPP4 (0.62) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL2606773 | 0.92 | DPP4 (0.62) | DPP4DPP7FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2108151 | 0.91 | DPP4 (0.61) | DPP4DPP7FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2105713 | 0.91 | DPP4 (0.61) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636224-A2 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | Prosidion Limited (GB) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004104001-A2 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | PROSIDION LIMITED (GB) | 2004-12-02 | — | — | WO | disclosed |