SCHEMBL5787376

SCHEMBL5787376

COc1ccc(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 8/20 0.61
▸ SLC5A1 P13866 6/20 0.61
▸ NPC1 O15118 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ TYR P14679 1/20 0.56
▸ ACHE P22303 1/20 0.54
▸ CD209 Q9NNX6 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9001307 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL11940290 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL11891009 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL23266197 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL15925919 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL23266259 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL7936422 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL5787383 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL11026136 1.00 SLC5A2 (0.61) SLC5A2SLC5A1NPC1RAB9ATYR
SCHEMBL6225078 0.99 SLC5A2 (0.59) SLC5A2SLC5A1NPC1RAB9ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325937-B2 Glycoside compound and preparation method therefor, composition, application, and intermediate SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2022-05-10 — — US disclosed
EP-3819303-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE Shanghai Hutchison Pharmaceuticals Limited (CN) 2021-05-12 — — EP disclosed
US-20210115082-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2021-04-22 — — US disclosed
WO-2006007634-A1 PROCESSES AND INTERMEDIATES CERYLID BIOSCIENCES LTD (AU) 2006-01-26 — — WO disclosed
EP-0650492-A1 REDUCING INFLAMMATION BY TIME DEPENDENT ADMINISTRATION OF OLIGOSACCHARIDES GLYCOSIDES RELATED TO BLOOD GROUP DETERMINANTS ALBERTA RESEARCH COUNCIL (CA) 1995-05-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11325937-B2 Glycoside compound and preparation method therefor, composition, application, and intermediate VEGFA, FLT4, FLT1 SLC5A2 897/4885SLC5A1 431/4885NPC1 3350/4885
US-20210115082-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE VEGFA, FLT4, FLT1 SLC5A2 897/4885SLC5A1 431/4885NPC1 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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