Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ADCY10 | Q96PN6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789203 | 0.83 | PTGDR2 (0.39) | PTGDR2CCR2CCR5CCNE2CDK4 | |
| SCHEMBL5749535 | 0.81 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL5750211 | 0.81 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL5751408 | 0.81 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL5751780 | 0.79 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL5748535 | 0.79 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL5753886 | 0.78 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL5749373 | 0.76 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL5753104 | 0.76 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL5752040 | 0.75 | PTGDR2 (0.48) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299361-B1 | PYRAZOLE DERIVATIVES | PFIZER LTD (GB) | 2006-07-19 | — | — | EP | claimed |