Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 20/20 | 0.85 |
| ▸ | TACR2 | P21452 | 1/20 | 0.85 |
| ▸ | TACR1 | P25103 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789978 | 1.00 | TACR3 (0.85) | TACR3TACR2TACR1 | |
| SCHEMBL6023627 | 0.93 | TACR3 (0.86) | TACR3TACR2TACR1 | |
| SCHEMBL2479624 | 0.92 | TACR3 (1.00) | TACR3TACR2TACR1 | |
| SCHEMBL2479054 | 0.92 | TACR3 (1.00) | TACR3TACR2TACR1 | |
| SCHEMBL2479210 | 0.92 | TACR3 (1.00) | TACR3TACR2TACR1 | |
| SCHEMBL2474737 | 0.92 | TACR3 (1.00) | TACR3TACR2TACR1 | |
| SCHEMBL2473336 | 0.92 | TACR3 (1.00) | TACR3TACR2TACR1 | |
| SCHEMBL5791165 | 0.89 | TACR3 (0.79) | TACR3TACR2TACR1 | |
| SCHEMBL5790475 | 0.89 | TACR3 (0.79) | TACR3TACR2TACR1 | |
| SCHEMBL5790528 | 0.88 | TACR3 (0.85) | TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016884-A9 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2006-03-16 | — | — | WO | disclosed |