Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159007 | 0.99 | CTSA (0.36) | CTSAKDM4EFFAR4TP53HPGD | |
| SCHEMBL5789396 | 0.89 | MAPK10 (0.37) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| SCHEMBL5784435 | 0.87 | SLC2A1 (0.36) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| SCHEMBL5783871 | 0.87 | SLC2A1 (0.36) | CTSAKDM4EFFAR4TP53HPGD | |
| SCHEMBL5785304 | 0.87 | KDM4E (0.40) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5784634 | 0.87 | SCN5A (0.34) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5782174 | 0.87 | KDM4E (0.35) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| SCHEMBL5783700 | 0.86 | CYP1A2 (0.36) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| SCHEMBL5785621 | 0.86 | TP53 (0.37) | KDM4EFFAR4TP53HPGDSMN1; SMN2 | |
| SCHEMBL5782315 | 0.86 | KDM4E (0.39) | KDM4EFFAR4TP53HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270577-B1 | FUROISOQUINOLINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-12-06 | — | — | EP | disclosed |