Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915005 | 0.87 | SRD5A2 (0.61) | SRD5A2FLT3POLBNPC1RAB9A | |
| SCHEMBL2313501 | 0.85 | SRD5A2 (0.61) | SRD5A2FLT3POLBNPC1RAB9A | |
| SCHEMBL5788215 | 0.83 | KMT2A (0.41) | SRD5A2POLBNPC1RAB9ADRD4 | |
| SCHEMBL5788221 | 0.82 | PTK2 (0.40) | SRD5A2POLBNPC1RAB9ADRD4 | |
| SCHEMBL30310576 | 0.77 | SRD5A2 (0.71) | SRD5A2FLT3POLBNPC1RAB9A | |
| SCHEMBL1144792 | 0.77 | SRD5A2 (0.71) | SRD5A2FLT3POLBNPC1RAB9A | |
| SCHEMBL5785835 | 0.77 | PARP1 (0.46) | LMNAMAPT | |
| SCHEMBL24020490 | 0.75 | SRD5A2 (0.67) | SRD5A2FLT3POLBNPC1RAB9A | |
| SCHEMBL30397127 | 0.75 | SRD5A2 (1.00) | SRD5A2FLT3POLBNPC1RAB9A | |
| SCHEMBL914722 | 0.75 | SRD5A2 (1.00) | SRD5A2FLT3POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-A2 | CHEMOKINE RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005077932-A2 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2005-08-25 | — | — | WO | disclosed |