SCHEMBL578973

SCHEMBL578973

C[C](F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7024179 0.76
SCHEMBL15005589 0.76
SCHEMBL579123 0.74
SCHEMBL727734 0.70
SCHEMBL1537249 0.70
SCHEMBL193302 0.70
SCHEMBL4730422 0.70
SCHEMBL31328382 0.70
SCHEMBL24291 0.67
SCHEMBL4362333 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042495-B2 MAP4K1 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2024-07-23 US claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
EP-4132650-B1 DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS UCB Biopharma SRL (BE) 2024-06-12 EP claimed
US-11878020-B2 Modulators of Rho-associated protein kinase REDX PHARMA PLC (GB) 2024-01-23 US claimed
CN-111655681-B Heterocyclylamino-substituted triazoles as modulators of Rho-related protein kinases 莱德克斯制药公共有限公司 2024-01-05 CN claimed
EP-4261217-A9 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-12-27 EP claimed
CN-117126078-A Compounds and application thereof in treating hDHODH-mediated diseases 四川大学 2023-11-28 CN claimed
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP claimed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO claimed
EP-3766882-B1 PHTHALAZINE ISOXAZOLE ALKOXY DERIVATIVES, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF SHANGHAI SIMR BIOTECHNOLOGY CO LTD (CN) 2023-08-23 EP claimed
EP-1831145-A1 SUBSTITUTED OXYARENES Bayer CropScience Aktiengesellschaft (DE) 2007-09-12 EP claimed
WO-2007090434-A1 SUBSTITUTED ARYL OXIMES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-08-16 WO claimed
JP-2007516249-A 2007-06-21 JP claimed
EP-1694682-A1 7-AMINO-5-HALOPYRAZOLOPYRIMIDINES WITH A FUNGICIDAL ACTION Bayer CropScience AG (DE) 2006-08-30 EP claimed
WO-2006069685-A1 SUBSTITUTED OXYARENES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-07-06 WO claimed
WO-2005056557-A1 7-AMINO-5-HALOPYRAZOLOPYRIMIDINES WITH A FUNGICIDAL ACTION BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-06-23 WO claimed
EP-0861235-A1 SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS PFIZER INC. (US) 1998-09-02 EP claimed
WO-1997008144-A1 SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS PFIZER PHARMACEUTICALS INC. (JP) 1997-03-06 WO claimed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US claimed
EP-0073437-B1 DYED POLYESTER FIBER COMPOSITE STRUCTURE TEIJIN LIMITED (JP) 1987-05-20 EP claimed