Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664842 | 0.86 | HTT (0.43) | KDM4EHTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL5789731 | 0.79 | — | — | |
| SCHEMBL1149811 | 0.77 | — | — | |
| SCHEMBL17165003 | 0.70 | — | — | |
| SCHEMBL8141439 | 0.68 | KDM4E (0.32) | KDM4ECYP2C9HTTLMNASMN1; SMN2 | |
| SCHEMBL17682476 | 0.67 | — | — | |
| SCHEMBL2537422 | 0.66 | — | — | |
| SCHEMBL2534494 | 0.65 | — | — | |
| SCHEMBL10075548 | 0.64 | CYP2C9 (0.32) | CYP2C9HTTKMT2AHPGD | |
| SCHEMBL8860887 | 0.63 | TSHR (0.33) | CYP2C9HTTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016237-A2 | HETEROCYCLIC DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-16 | — | — | WO | claimed |
| CN-115160305-A | Amide compound containing 4, 5-dihydroisoxazole, salt thereof, preparation method and application | 华东理工大学 | 2022-10-11 | — | — | CN | disclosed |
| WO-2010058423-A2 | NOVEL ANTIMICROBIALS | PANACEA BIOTEC LTD. (IN) | 2010-05-27 | — | — | WO | disclosed |